68m. ERCP, ?sclerosing cholangitis
1. On the H&E focus on the portal tracts – there is one very nice example of onion skin fibrosis around a bile duct and another portal tract shows a bile duct scar (look for the unaccompanied artery). These appearances are not specific but in the right context are typical of PSC.
2. The trichrome confirms the fibrosis (several artefacts on this slides too – get used to them!).